Topical corticosteroids

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Topical Corticosteroids: Pharmacology

Topical corticosteroids are widely used for inflammatory and hyperproliferative disorders in dermatology. Numerous topical corticosteroids with high local activity have been developed over the years, with a focus to develop drugs with high efficacy locally and minimum risk for adverse drug reactions. They are available in a number of formulations. Their therapeutic effects are a result of their...

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Topical corticosteroids in dermatology.

Since their introduction, topical corticosteroids have become indispensable in the treatment of various dermatoses. Hydrocortisone was the first compound. Modifications in the basic structure generated in vivo activity and thus different topically active compounds were discovered. Apart from the Stoughton vasoconstrictor assay, various other methods are used for potency assessment of topical co...

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Topical corticosteroids and fungal keratitis.

The incidence of experimentally produced keratitis with Candida albicans was studied in traumatized rabbit eyes; these eyes, 23 out of 30 treated with 1 per cent hydrocortisone drops, 16 out of 30 treated with 1 per cent medrysone drops, and 12 out of 30 treated with control drops without corticosteroid, developed infection as demonstrated by culture of corneal tissue. The increased number of i...

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Intraocular Pressure Response to Topical Corticosteroids.

The intraocular pressure response to topical betamethasone appears to be genetically determined. A study of patients with primary open-angle glaucoma, their relatives, glaucoma suspects, and volunteers shows three populations as to degree of responsiveness. It is suggested that these are the phenotypes which relate to the homozygous poor responder (nn), the heterozygous responder (ng), and the ...

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Majocchi's Granuloma after Topical Corticosteroids Therapy

Majocchi's granuloma (MG) is an unusual but not rare dermatophyte infection of dermal and subcutaneous tissues. Dermatophytes usually result in the infections of hair, epidermis, and nail, and are rarely involved in deep cutaneous and subcutaneous tissues. Now it is considered that MG includes two forms: one is a small perifollicular papular form and the other is a deep subcutaneous nodular for...

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ژورنال

عنوان ژورنال: Australian Prescriber

سال: 2014

ISSN: 0312-8008,1839-3942

DOI: 10.18773/austprescr.2014.023